1909 - Used as a food preservative for cold storage of meats
1939 - Was found to prevent the growth of yeast & mold during the storage of fruits
History of GRAS Status of Ozone
1982 - FDA GRAS declaration for ozone use in bottled water
1995 - FDA GRAS for ozone use in bottled water renewed without change
1997 - Industry Expert Panel declares ozone GRAS and meets FDA requirements. Regulators have the option to later add control on ozone use.
1999 - USDA rejects an ozone use protocol for meats, cites 1982 GRAS declaration for water where FDA stated "any other use must be regulated by a Food Additive Petition."
2000 - Food Additive Petition, that addresses both water and air use of ozone, under preparation. FDA estimates approval will occur within six months of submission of the Petition
Status of Ozone in the Food Industry
1982 - O3 declared GRAS for treatment of bottled water (Federal Register, Vol. 47, No. 113, November 5, 1982)
1997 - Expert panel report : Evaluation of the history and safety of ozone in processing foods for human consumption. Vol. 2 : Abstracts. Electric Power Research Institute, Palo Alto, CA. R & D Enterprise, Inc. / GRAS self declaration (Federal Register, v. 62 #74, April 19, 1997)
2000 - FDA and USDA approval granted.
EPA - Disinfection By-Product Rules (DBPR)
2000 - 2004: Implementation Stage
Ozone is EPA listed as DBPR compliant
EPA Air Quality Rulings
1979 - EPA promulgated an ozone standard of 0.12-ppm 1-hr ozone standard (44 Federal Register 8202, February 8,1979)
1997 - EPA established an ozone standard of 0.08-ppm, measured over an 8-hr period (62 Federal Register 38856)
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